Combined Simultaneous Kidney/bone Marrow Transplantation! Ron Shapiro,2 Abdul
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چکیده
Further investigation is necessary to determine the potential clinical impact of hyperlipidemia on transplant patients. Specifically, the development of atherosclerotic complications, including cerebrovascular, peripheral vascular, and cardiovascular morbidity and mortality, must be compared in patients with normal versus abnormal lipid profiles. These findings do not suggest that hyperlipidemia in transplant recipients is inconsequential but rather that therapy should probably be based on the presence of other cardiovascular risk factors because when the general population of transplant recipients is considered, hyperlipidemia as a single entity is not a significant determinant of graft or patient survival. Currently, we encourage reduction of cardiovascular risk factors with an exercise program, low cholesterol diet, elimination of smoking, weight reduction in overweight patients, and aggressive blood pressure control. Pharmacotherapy is initiated in patients with other concomitant cardiovascular factors when moderate to high risk hypercholesterolemia persists despite the application of the aforementioned measures.
منابع مشابه
Combined kidney/bone marrow transplantation--evidence of augmentation of chimerism.
Recent studies on patients who have maintained stable hepatic and renal allograft function for 10-28 vears have revealed systemIc microchimerism in all (1. 2l. With the belief that this is the essential mechanism of allograft acceptance. we sought to augment the spontaneous chimerism in newly transplanted recipients. and began a program of combined simultaneous kidney/bone marrow transplantatio...
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تاریخ انتشار 2010